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Karisma Rh Collagen · Skin rejuvenation

Early lines and acne scars, renewed with collagen your skin recognises.

Early lines, acne scars, skin that lost its bounce. Karisma gives your skin recombinant collagen as building blocks to renew itself over a short course.

Your conversation stays between you and our all-female team.

30–45 min per session, incl. numbing
24–48 hours for injection marks to settle
Doctor-led skin assessment before anything
All-female medical team, always

Karisma, in one paragraph

Karisma at Klinik Amisi is an injectable biostimulator combining recombinant human collagen with hyaluronic acid, designed to support skin quality and texture, often considered for early prevention and acne scar improvement. A session takes 30 to 45 minutes including numbing, with a typical course of 3 sessions spaced 3 to 4 weeks apart and periodic maintenance. Downtime is usually mild, with small bumps, redness or pinpoint marks that settle within 24 to 48 hours.

You're not alone

Skin slows down early. Long before it shows its age.

Collagen production starts to taper in your mid-twenties, quietly, years before the first lines settle in. Most women notice it the same way: skin that looks a little flatter by evening, texture that used to bounce back, scars that stopped fading.

Your skin still knows how to rebuild. Sometimes it just needs the raw material to start.

Does this sound like you?

Karisma is made for these exact concerns.

Early fine lines and loss of firmness
Dull skin that has lost its bounce
Mild to moderate acne scars
Uneven texture and rough-looking skin
Skin starting to look tired in your late 20s or 30s
A preference for non-animal-derived collagen
When it's not for you: we don't offer Karisma during pregnancy or breastfeeding, with an active skin infection, open wound or cold sores in the treatment area, or with a known allergy to any component. Autoimmune, bleeding or clotting conditions need medical clearance first. Our doctor screens all of this at consultation, and will tell you honestly if a different treatment fits better.

Three effects, one session

Formulated by Taumedika, Italy, using recombinant human collagen produced through NEOSILK biotechnology, with no animal source.

01 · Rebuild

Regenerate

Recombinant human collagen acts as a precursor, signalling your fibroblasts to produce fresh collagen of their own.

02 · Restore

Refine

A biorestorative soft-filler base helps restore structure and soft contour for firmer, more refined skin.

03 · Hydrate

Plump

High-molecular-weight hyaluronic acid holds water in the skin for a hydrated, plumper look from day one.

Karisma product

How it works

A short session. Your skin rebuilds the rest.

After topical numbing, our doctor places Karisma into the upper layers of the skin in small, controlled points. The recombinant collagen gives fibroblasts a precursor to work with, while hyaluronic acid hydrates, so collagen and skin quality keep building in the weeks after each session.

Recombinant human collagen α1High-molecular-weight hyaluronic acidCarboxymethyl celluloseNEOSILK biotechnologyNon-animal, non-crosslinkedCE-marked medical device

What recovery really looks like

Your week after treatment.

Same day Walk out, carry on

Small bumps at the injection points are expected. Skip heavy makeup for the rest of the day.

Day 1–2 Let it settle

Bumps soften and redness fades. Avoid strenuous exercise, saunas and very hot showers for 24 hours.

First week Be gentle

Skip strong actives, exfoliants and facial massage for 48 hours. Daily SPF 50+ from day one.

The weeks after It keeps building

Collagen builds gradually, and firmness, texture and glow improve over your course.

A typical course is around 3 sessions spaced 3 to 4 weeks apart, and your doctor plans yours with you at consultation. No fixed packages, no pressure.

Doctor-led, female-led care

Advanced collagen care. In careful hands.

  • Every doctor, nurse and front-desk team member is a woman.
  • Private consultation rooms. Your visit and details stay discreet.
  • A doctor examines and screens you before any treatment is planned.
  • Four branches across the Klang Valley: Bangi, Putrajaya, Shah Alam, KL.
Book a private consultation

Questions, answered plainly

What women ask us most.

What is Karisma?
Karisma is an injectable biostimulator made by Taumedika in Italy, combining recombinant human collagen with high-molecular-weight hyaluronic acid and carboxymethyl cellulose, produced under NEOSILK biotechnology. It is designed to support skin quality, texture and gentle restoration rather than to add bulk volume.
How is the collagen sourced?
The collagen used in Karisma is recombinant human collagen, meaning it is produced through laboratory biosynthesis rather than from animal sources. This may be relevant for patients who prefer a non-animal-derived option.
Is this a filler?
No. Karisma is a collagen and hyaluronic acid biostimulator, not a volumetric dermal filler. It is designed to support skin quality and texture rather than to add bulk volume or change facial proportions.
Is the treatment painful?
Topical numbing cream is applied before the session to keep the experience comfortable. Most patients describe mild stinging or pressure during the injections.
How quickly will I see a difference?
Some patients notice changes in skin quality within a few weeks, with continued improvement over the course. Acne scar improvement, if applicable, builds more gradually. Individual results vary.
How long do results last?
Improvement from a full course can typically last around 6 months for many patients. Maintenance sessions are usually part of the long-term plan. Your doctor will outline a realistic schedule at consultation.

Not sure what your skin needs?

Tell us what you've been noticing, in Malay or English. Our team will let you know whether Karisma, a different treatment, or simply a consultation is the right first step.

WhatsApp us — it stays private